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misfitz
Posts: 41
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Posted: Thu May 27, 2004 1:01 am Post subject: |
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| the creams have helped my skin about 80% overall. When I run my hands over my face, it 'feels' smooth though i still have spots from hyperpigmentation/scars and The itchy red spots are visually noticeable. |
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Lenore Moderator Posts: 2486
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Posted: Thu May 27, 2004 5:03 am Post subject: |
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It's great to hear of people clearing up, but I do have some concerns about the products. One is that metronidazole is an antibiotic, and my experience with topical antibiotic lotions is that they worked great for like 3 months or so, and then stopped working, apparently because resistant bacteria had formed (which is a problem with all antibiotics that I know of). Also, I have been reading about an anti-mite soap from China for a long time (probably the Face Doctor one), since many many years ago, and it seems to me if it was so dramatically effective on a longterm basis, that word would have spread about it and that dermatologists would be using it. It has been around for a long time though, so maybe people are using it repeatedly and having success with it.
The other thing that concerns me is that some supposedly "natural and herbal" medicines that came from China were discovered to actually contain Western drugs in them, some of them addictive (like Valium, for example). Two doctors told me about this danger. A friend once bought me a supposedly herbal sleep medicine from China, Jin Bu Huan, which worked so well, that I started to feel suspicious about it being just herbal. Sure enough, when I mentioned it to a friend of mine who is a homeopathic Doctor of Oriental Medicine, he said that this pill did actually contain a drug and was not herbal. Anyway, I know these products are topical, but I would have some concern as to whether there might be cortizone or other steroids in them that would calm inflammation in the short run, but then cause worsening of the acne in the long-run (as topical steroids can do). This is a remote possibility, but I just became suspicious of Chinese herbal medicines from my experience with the sleeping pill.
I don't know if these are a different type of mite, but I've always been concerned about there being dust mites in my pillows (I have some older pillows). A friend told me that putting the pillows in a hot dryer will kill the mites. I think that most pillows can be laundered in a large capacity washing machine at a laundrymat and then dried there also. I'm concerned, though, that any remaining dampness inside the pillow might harbor mold or something. There are special pillow cases to keep the mite dust contained (I think the allergens are from their excrement or the mite corpses). One article claimed that something like 10 or 15% of the weight of a pillow could be actually made up of mites and mite corpses (oh, God, that's disgusting, isn't it?). I know that mites can cause allergic reactions, but I've never read about them being implicated in acne, except in those ads for Chinese soaps. In the Dr. Murad commercials, he talks about there being many different skin conditions that look like acne but aren't actually acne. Perhaps the problem is that the traditional acne medicines, like benzoyl preoxide e.g., only work for true acne, and not for the other look-alike conditions.
Here's a previous thread on the board about Demodex mites:
http://www.clearskin.net/viewtopic.php?t=4313 |
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gerald
 Posts: 77
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Posted: Thu May 27, 2004 10:59 am Post subject: |
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Well, thanks for your info lenore...I must say i am easily influenced and easily awed. Your post does have its point.
I started my cream last night. It does feel very comfortable on me. The minty feel was great but today i noticed that the two bumps i have seems to be much crusty in colour and seems more obvious.
So that means the metronizade in the crem is actually a form of a/biotic? So do you mean that it is a wrong move to use this cream then?
One thing that confuses me is why the price is so extravagant when the packaging is so simple... Plus, they come from two different companies.
I surfed the website www.xmfl.com.cn but i cont understand the language...i will ask my friend to read them for me tomorrow.
But i really pray that my problem is demodex. For now my t-zone is kinda fested with dry patches....something like fungal infections...but nothign worst thoug...jhust dryness on the forehead.
I will cross my finger that this thing will work on me...btw, is there any long term demodex solutions users here?
cz440, u seem to know walter well when u say he's busy ... |
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Lenore Moderator Posts: 2486
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Posted: Thu May 27, 2004 5:08 pm Post subject: |
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Gerald, I really don't know whether this product works or not. It might be just the ticket for some people, I just don't know. I just know what my experience was with topical antibiotics like Cleocin-T and others -- they worked famously for a few months and then they stopped working, and the acne came back in full force or even worse. Now these mite products contain a lot of other ingredients, so perhaps by the time the antibiotic stops working, the skin will have cleared from the other ingredients, I just don't know.
You might want to check out other acne boards, like http://www.absoluteacneinfo.com/index.html , and the one at http://www.healthboards.com and do a search on those boards and see whether people have tried these products and what results they had. |
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zigzag
Posts: 42
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Posted: Thu May 27, 2004 7:21 pm Post subject: |
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I've also used antibiotics and indeed they do stop working, however I have read that this medicine is known not to stop working at any point -- Walter should be able to explain why... I will try to refer him to here.
As of today my face is clear and only marks remain  |
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misfitz
Posts: 41
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Posted: Fri May 28, 2004 12:15 am Post subject: |
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Metronidazole is technically an Anti-Fungal, though it has some antibiotic properties. There is a difference, because fungi are actually eukaryotic (all bacteria are prokaryotes). Anti-Fungals can be nasty because its tough to get a really specific one that wont act on the good eukaryotes (your body cells) vs. the bad ones.
The Xin Fumanling cream contains Metronidazole and as such should be used carefully. After treatment, the usual protocol is to eventually phase out the xfml cream and go into a maintenance program with the zhongzou cream only. Walter could probably explain it better, but the 2 creams are manufactured to stringent quality controls and as such ingredients like corticosteroids cannot be in the mixture without being stated. I cannot vouch for longterm effectiveness but you really can't be sure of anything's longterm efficacy on an individual basis. I find the Zhongzou cream to be far superior and I apply XFML cream about once every 2 days these days.
Like Lenore says, if you've tried EVERYTHING, and you've got the symptoms, then give this a try. Its not going to work for everyone, but all I've heard are success stories so far.
But I just wanted to make the distinction that the products do NOT work primarily via an antibiotic mechanism. Sulfur is the primary ingredient in the Zhongzou cream, but I've used sulfur resorcinol before to no avail. I've used all the antibiotic creams in the world and NONE worked. The demodex solutions creams are also used for rosacea much of the time, which isn't thought of as a bacterial problem. |
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Lenore Moderator Posts: 2486
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Posted: Fri May 28, 2004 5:39 am Post subject: |
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Misfitz wrote:
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| Like Lenore says, if you've tried EVERYTHING, and you've got the symptoms, then give this a try. |
I don't recall making a statement like that Misfitz.
Here's a description of metronidazole I got from the Internet:
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| DRUG CLASS AND MECHANISM: Metronidazole cream is a topical (applied to the skin) preparation of the antibiotic metronidazole. It is used for reducing the swelling and redness caused by acne rosacea. The mechanism through which metronidazole cream reduces the symptoms of acne rosacea is not known. |
I'm wondering if these mite products might be more effective for acne rosacea than regular acne vulgaris. It seems like there are more references to the mites being connected to rosacea than to acne vulgaris. I really don't know though. I would like to know how people do on these treatments over a 6 month period or longer. I'm not trying to rain on anyone's parade here. If these products have been selling for all these years, it seems like they must be helping some people. I really don't know much about them or about mites in connection with acne. |
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DanishDude
 Posts: 156 Location: Copenhagen, Denmark
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Posted: Fri May 28, 2004 6:05 am Post subject: |
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Hello Lenore and others
I have been diagnosed with rosacea for about 5 years now. First of all - it is called "rosacea" and not "acne rosacea" since many products related to acne make rosacea patients breakout severely (eg. Benzoyl Peroxid). It is a common misunderstanding among doctors etc.
Second - if you want to know more about Demodex Mites in relation to rosacea I recommend the following website: www.rosacea.ii.net/toc.html When you enter the page you should choose "Theories" and then "Demodex Mites".
The www.rosacea.ii.net also has a discussion board on yahoo.com where they at the moment discuss Demodex mites. Maybe we should exchange information.
Best regards
DD  |
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misfitz
Posts: 41
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Posted: Fri May 28, 2004 6:51 pm Post subject: reply |
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| Lenore wrote: |
| Gerald, I really don't know whether this product works or not. It might be just the ticket for some people, I just don't know. |
Sorry lenore. I mistook this statement as you acknowledging that it might make a good treatment for people who have'nt had luck with other therapies. I didnt mean it as a quote per se, but I read to much into the sentence.
In regards to Metronidazole, it's almost never prescribed as a topical antibiotic in the classical sense a la the macrolides (erthryomycin, clarithryomycin, etc..), tetracycline and minocycline, which are the most popular drugs for acne. It does have antibiotic properties, but its not used that way because there are more effective antibiotics out there. The number one prescribed use for topical metronidazole is for rosacea which is not a bacterial disease. Most sites will list it as an antibiotic, then paradoxically say it works against bacteria like amebiasis, trichomoniasis, and giardiasis, which are not bacteria, but actually parasites. The difference between a parasite and amoeba is that one is a eukaryote and the other is a prokaryote. See my last post if you want to read more about it. I assume the internet literature classification takes 'antibiotic' to mean effectiveness vs. microscopic organisms, and not the true definition of anti-prokaryotic drug (which is what a physician will prescribe when the dish out antibiotics). The internet is a wonderful tool, but it's almost like a pamphlet in terms of the information it makes available to the patient. I don't mean to chastise you at all, I thoroughly enjoy your efforts to help clarify matters. So yes, you are right in that it has antibiotic properties, but it doesn't work like any other acne topical antibiotics.
The creams might only be effective in conditions that mimic acne... which also might be why my situation has been improved immensely by the creams (and why traditional acne therapies did zilch). I don't have acne rosacea, and yes the link between demodex mites and acne rosacea is concrete (correlational for now, not causal).
I realize there is a fair amount of skepticism out there, but we should realize that everyone's acne is different and will respond to various therapies based on their acne's cause. Diet works for some, Accutane for others, etc. But lets not make the mistake that what works for me will work for you and vice versa. Because of that, the only true cure for acne will be entirely symptomatic- By stopping the mechanism of papule formation (which is basically the same inflammatory response regardless of etiology), you'll nip the disease.
so again, use the creams on your own caution. I'll continue to update y'all on how I'm doing but don't expect a cure all. I've tried everything incl radical diet changes (wai diet-1 month, gluten free, no carb, no fat, etc..), cleanses (4 liver cleanses, bowel, kidney, parasite.. no effect), accutane, topicals, you name it, all which didn't work. |
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misfitz
Posts: 41
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Posted: Fri May 28, 2004 6:53 pm Post subject: |
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| by cure for acne, i mean, UNIVERSAL cure for acne- that it works for ALL people. a lot of people have found their personal cure which hasnt helped others. |
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gerald
 Posts: 77
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Posted: Tue Jun 01, 2004 11:14 am Post subject: |
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Umm,
I am confused now. I dont want this thing to come back worse ever...I feel really comfortable with the creams though...
But now after 6 days, i get breakouts here and there. Some are subsiding some small ones are growing....they have heds though as opposed to the ones i normally have before..
I have my singing auditions next week and whole lots of interviews...I am worry if these dont go away in a week.
I am indecisive now.... |
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misfitz
Posts: 41
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Posted: Wed Jun 02, 2004 2:18 pm Post subject: 6 week update |
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Today is an awesome day. I don't have any cystic acne anymore, and the rest of my face looks good. I think I'm gonna start some microdermabrasion or something for my scars. I'm happy that I can even focus on my scars (I was more concerned with active acne). The red spot breakout has subsided significantly and my face does not feel itchy all the time. Hopefully things continue to get better. I wish i tried this treatment before others preventing the ravages of past scars.
Gerald- based on the demodex boards, i'd say that you are probably going to have some breakouts. Some have said it'll last for 2 months. I've personally found this to be the case. But the breakouts I've gotten haven't been scar-inducing or cystic, so thats a plus. Its DEFINITELY NOT an accutane like breakout (where every cyst in a 100 m radius decide to show up for a party on your face). I know you're worried, but what can you do? keep with the treatment, and hope that it doesn't interfere with your singing audition... alternately you can stop, wait until after your audition and give your skin some time to heal. Was anything working for you before? Maybe you should stick with it until at least after your singing. |
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gerald
 Posts: 77
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Posted: Thu Jun 03, 2004 7:57 am Post subject: |
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I am clear before this with very very minor white heads which don't bother me much but now after 8 days with the cream, I am getting a big bump which has white pus on my left cheeks and on my right jaw...I also noticed some red spots which i dunno as pimples or not nearby my cheekbones which has been totally clear for as long as i remember...I hate to think but how come i am getting more spots with the cream? i use only cetaphil to clean up everyday so maybe it is not cleansing the zhong zhou enough? I think it's a lil bit sicky and perhaps comedogeinic? The Zhong Zhou I mean. my audition is next tuesday....S**t and these spots appears. Damn...i gues i am gonna wear some nice two way cake for that day...but imagine the journey to the venue could been hellish...
I dunnno what o expect on my skin until tuesday...But i am kinda worried...some of the spots are disappearing but hey of course spots disappear yeah...it's just whether my body system is healing it or the creams...Arrrrr I feel like crying.
U mean it's 2 months before u see definite clarity misfits? Whatabout the others? |
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misfitz
Posts: 41
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Posted: Thu Jun 03, 2004 11:47 am Post subject: |
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I once read every message on the demodex solutions board, and it seemed the lucky ones had it work immediately, but on average, it takes about 1 month for the breakouts to die down a lot, and longer to become totally clear. at 1.5 months, My skin is pretty good- almost free from breakouts.
I'm interested in yur treatment history because from what I've read, the creams seem to work well in cases where all other standards forms of therapy (accutane, b5, diet, etc..) have not worked. If you havent tried those other things, then I'm not sure if your acne is the right "type" for this treatment. You might find success with those other options. My history included periods where I would feel this really itchy spot on my face followed by a red inflammatory mark (almost like an insect bite), which went away in a couple of hours. have you ever had this?
Its been a long process for me but I feel like I've found my holy grail. =b |
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zigzag
Posts: 42
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Posted: Fri Jun 04, 2004 7:53 pm Post subject: |
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| gerald wrote: |
| U mean it's 2 months before u see definite clarity misfits? Whatabout the others? |
I saw great results right away, but then when i missed using it for 2 weeks it turned bad again, then having resumed, now at around 2 months i guess? I am having no new breakouts at all and my skin is healing. I had a minor little bump above my lip but it went away before it became anything at all, so whatever I'd not worry much about the cream having a major negative impact on your skin, it seems light enough to me... and my skin is very sensitive. Just keep using it... also I doubt a few pimples will make your audition any worse!
| misfitz wrote: |
| My history included periods where I would feel this really itchy spot on my face followed by a red inflammatory mark (almost like an insect bite), which went away in a couple of hours. have you ever had this? |
Yes, this is what I had!!! and very very rarely still have, but then i guess its okay for it to happen once in a while anyway... but it has reduced so much. I really can't believe how well this stuff works, and yes, me too, I've found my holy grail  |
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